Thursday, 15 Oct 2026

Popular erectile dysfunction pill may deliver additional boost to aging men

Tadalafil boosted muscle precursor cell survival in a lab study, but researchers say the active Cialis ingredient also delayed mature muscle development.


Popular erectile dysfunction pill may deliver additional boost to aging men

The study, published in the journal Molecular Biology Reports, tested the drug on mouse muscle cells in a laboratory.

Over a seven-day period, the researchers looked at how the drug affected muscle cell growth, survival and development.

Tadalafil was found to increase the number of muscle precursor cells, which are involved in the early stages of muscle formation, and helped more of them survive.

Despite these positive outcomes, the research found that tadalafil delayed the development of fully mature muscle cells.

This suggests that the drug could create and maintain more cells involved in muscle regeneration but does not indicate an increase in muscle size and function in humans.

Because the study was conducted in mouse models, the results may differ when applied to humans, posing a limitation to the study findings.

Study co-author Dr. Cristina Antinozzi, a researcher in the Endocrinology Unit at the University of Rome Foro Italico, said these findings represent an "encouraging look at how tadalafil might be repurposed to support muscle tissue repair and regeneration."

Dr. Kien Vuu, a radiologist and founder of VuuMD Performance and Longevity in Los Angeles, who was not involved in the study, agreed that this is an "intriguing early finding."

"That's a fascinating biological signal, but it's far from proving that Cialis builds muscle or improves recovery in people.

"Successful regeneration ultimately requires those cells to mature and form functional muscle tissue. This experiment didn't establish that outcome."

"However, this was a laboratory cell study, not a clinical trial," he said. "We need animal studies and eventually human trials examining actual muscle mass, strength, physical function and safety before drawing conclusions about clinical use."

"So, people should not take it for muscle-building based on these findings," he said.

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